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Key Legend

Locations in Red Color Represents – Core centers

Locations in Blue Color Represents – Vanguard centers

*Open to Patient Accrual

Asia

  1. Fu-Wai Hospital, Beijing, China*
  2. Jilin Heart Hospital, China*
  3. TEDA International Cardiovascular Hospital (TICH), Tianjin, Chinese Academy of Medical Sciences & Peking Union Medical College, China*
  4. Ruijin Hospital Shanghai Jiao Tong University School of Medicine, China
  5. Saitama Medical University, Japan*
  6. Tokyo Medical and Dental University, Tokyo, Japan*
  7. National Taiwan University Hospital, Taiwan*
  8. National University of Singapore*
  9. Severance Cardiovascular Hospital, Yonsei University College of Medicine*, South Korea
  10. Star Hospitals – Hyderabad, India*
  11. G Kuppuswamy Naidu Memorial Hospital , India*
  12. Seoul National University Hospital, South Korea*
Fu-Wai Hospital, Beijing, China

Beijing, China

Hiratsuka Kyosai Heart Center, Japan

Hiratsuka Kyosai Heart Center, Japan

Jilin Heart Hospital, China

Changchun, Jilin, China

Kurume University School of medicine, Fukuoka, Japan

Fukuoka, Japan

National Taiwan University Hospital, Taiwan

National Taiwan University Hospital, Zhongzheng District, Taipei City, Taiwan

Queen Alia Heart Institute, Amman Jordan

Queen Alia Heart Institute, Amman, Jordan

Saitama Medical University, Japan

Saitama Medical University, Japan

TEDA International Cardiovascular Hospital (TICH), Tianjin, Chinese Academy of Medical Sciences & Peking Union Medical College, China

61 3rd St, Binhai, Tianjin, China, 300457

Tokyo Medical and Dental University, Tokyo, Japan

Tokyo Medical and Dental University, Tokyo, Japan

Ruijin Hospital Shanghai Jiao Tong University School of Medicine

Shang Hai Jiao Tong Da Xue Yi Xue Yuan Dong Bu – Dong 11 Lou, Liu Bei Qu, Liu Zhou Shi, Guang Xi Zhuang Zu Zi Zhi Qu, China, 545002

National University of Singapore

21 Lower Kent Ridge Rd, Singapore 119077

Severance Cardiovascular Hospital, Yonsei University College of Medicine

50-1 Yonsei-ro, Sinchon-dong, Seodaemun-gu, Seoul, South Korea

Star Hospitals – Hyderabad, India

Survey No.74, Financial District, Nanakaramguda, Telangana 500008, India

G Kuppuswamy Naidu Memorial Hospital , India

Netaji Rd, Pappanaickenpalayam, Tamil Nadu 641037, India

Seoul National University Hospital, South Korea

101 Daehak-ro, Jongno-gu, Seoul, South Korea

Canada

  1. Hamilton General Hospital, Hamilton, Ontario, Canada*
  2. Sunnybrook Health Science, University of Toronto, Toronto*
  3. Université Laval, Quebec City, Quebec, Canada*
  4. University of Ottawa Heart Institute, Ottawa*
  5. Toronto General Hospital
  6. University Hospital of Montreal (CHUM)
  7. St. Boniface General Hospital / WHRA
  8. Montreal Heart Institute, Canada*
  9. Health Sciences North – Sudbury, Canada*
  10. Horizon Health Network – Saint John Regional Hospital – New Brunswick, New Brunswick, CA*
  11. Royal Victoria Hospital (McGill Univ Health Ctr), Canada
  12. St. Michael’s Hospital, Canada
Université Laval, Quebec City, Quebec, Canada

Université Laval, Quebec City, Quebec, Canada

Sunnybrook Health Science, University of Toronto, Toronto

Sunnybrook Health Science, University of Toronto, Toronto

Hamilton General Hospital, Hamilton, Ontario, Canada

Hamilton General Hospital, Barton Street East, Hamilton, Ontario, Canada

Toronto General Hospital

200 Elizabeth St, Toronto, ON M5G 2C4, Canada

University Hospital of Montreal (CHUM)

1051 Rue Sanguinet, Montréal, QC H2X 3E4, Canada

St. Boniface General Hospital / WHRA

409 Tache Ave, Winnipeg, MB R2H 2A6, Canada

Montreal Heart Institute, Canada

5000 Rue Bélanger, Montréal, QC H1T 1C8, Canada

Health Sciences North – Sudbury, Canada

41 Ramsey Lake Rd, Sudbury, ON P3E 5J1, Canada

Horizon Health Network – Saint John Regional Hospital – New Brunswick, New Brunswick, CA

400 University Ave, Saint John, NB E2L 4L2, Canada

Royal Victoria Hospital (McGill)

1001 Bd Décarie, Montréal, QC H4A 3J1, Canada

US

  1. Cleveland Clinic Foundation, Cleveland, OH.*
  2. Weill Cornell Medicine, New York Presbyterian Hospital Brooklyn, Brooklyn, NY.*
  3. Weill Cornell Medicine, New York Presbyterian Hospital Manhattan, New York, NY.
  4. Weill Cornell Medicine, New York Presbyterian Hospital Queens, Queens, NY.
  5. Baystate Health, MA*
  6. Allegheny General Hospital (Cardiovascular Institute) Pittsburg, PA*
  7. Icahn School of Medicine, Mount Sinai Hospital*
  8. University of Colorado
  9. University of Nebraska Medical Center
  10. Ohio State University*
  11. Lenox Hill Hospital(Northwell North Shore Campus/Lenox Hill Hospital/ Staten Island/ Southside), NY
Cleveland Clinic Foundation, Cleveland, OH

Cleveland Clinic Foundation: Gill Inderjit MD, Metrohealth Drive, Cleveland, OH, USA

Weill Cornell Medicine, New York Presbyterian Hospital Brooklyn, Brooklyn, NY

Weill Cornell Medicine, New York Presbyterian Hospital Brooklyn, Brooklyn, NY

Weill Cornell Medicine, New York Presbyterian Hospital Manhattan, New York, NY

Weill Cornell Medicine, New York Presbyterian Hospital Manhattan, New York, NY

Weill Cornell Medicine, New York Presbyterian Hospital Queens, Queens, NY

Weill Cornell Medicine, New York Presbyterian Hospital Queens, Queens, NY

Baystate Health, MA

2 Medical Center Dr STE 503, Springfield, MA 01107, USA

Allegheny General Hospital (Cardiovascular Institute) Pittsburg, PA

320 E North Ave, Pittsburgh, PA 15212, USA

Icahn School of Medicine, Mount Sinai Hospital

79-01 Broadway, Queens, NY 11373, USA

University of Colorado

Boulder, CO 80309, USA

University of Nebraska Medical Center

42nd and, Emile St, Omaha, NE 68198, USA

Ohio State University

281 W Lane Ave, Columbus, OH 43210, USA

Northwell Health Lenox Hill Hospital, New York, NY

Northwell Health Lenox Hill Hospital, New York, NY

Italy

  1. Ospedale Le Molinette, Torino*
  2. Anthea Hospital, Bari, GVM Care and Research – Villa Maria Hospital Bari, GVM Care and Research*
  3. Maria Cecilia Hospital GVM
  4. Humanitas Gavazzeni of Bergamo, Italy*
  5. European Hospital, Roma, Italy
  6. Fondazione Poliambulanza, Brescia, Italy
  7. Universita’ Cattolica del Sacro Cuore, Roma, Italy
Anthea Hospital, Bari, GVM Care and Research – Villa Maria Hospital Bari, GVM Care and Research

Anthea Hospital, Bari, GVM Care and Research – Villa Maria Hospital Bari, GVM Care and Research

European Hospital, Roma

European Hospital, Roma

Fondazione Poliambulanza, Brescia

Fondazione Poliambulanza, Brescia

Universita’ Cattolica del Sacro Cuore

Universita’ Cattolica del Sacro Cuore

Ospedale Le Molinette, Torino

Ospedale Le Molinette, Torino

Maria Cecilia Hospital GVM

Via Corriera, 1, 48033 Cotignola RA, Italy

Humanitas Gavazzeni of Bergamo, Italy

Via Mauro Gavazzeni, 21, 24125 Bergamo BG, Italy

Germany

  1. Robert-Bosch Hospital, Stuttgart*
  2. HDZ NRW Bad Oeynhausen Germany*
  3. University Hospital Erlangen*
  4. Heart Center (Herzzentrum) Leipzig Germany*
  5. Duisburg Heart Center, Germany*
  6. Essen University, Germany*
  7. Frankfurt University, Germany*
  8. Krankenhaus der Barmherzigen Brüder Trier
  9. Düsseldorf University
  10. Jena University Hospital
  11. University Medical Center of Goettingen
  12. Universitäts-Herzzentrum Bad Krozingen, Germany*
  13. University Hospital of Giessen and Marburg, Germany
Bad Oeynhausen Hospital

Bad Oeynhausen Hospital

Düsseldorf University, Düsseldorf

Düsseldorf University, Düsseldorf

Robert-Bosch Hospital, Stuttgart

Robert-Bosch Hospital, Stuttgart

Universitätsklinikum Gießen und Marburg GmbH, Giessen

Universitätsklinikum Gießen und Marburg GmbH, Giessen

HDZ NRW Bad Oeynhausen Germany

Georgstraße 11, 32545 Bad Oeynhausen, Germany

University Hospital Erlangen

Maximilianspl. 2, 91054 Erlangen, Germany

Heart Center (Herzzentrum) Leipzig Germany

Strümpellstraße 39, 04289 Leipzig, Germany

Duisburg Heart Center, Germany

Gerrickstraße 21, 47137 Duisburg, Germany

Essen University, Germany

Hufelandstraße 55, 45147 Essen, Germany

Frankfurt University, Germany

Nibelungenpl. 1, 60318 Frankfurt am Main, Germany

Krankenhaus der Barmherzigen Brüder Trier

Nordallee 1, 54292 Trier, Germany

Düsseldorf University

Universitätsstraße 1, 40225 Düsseldorf, Germany

Jena University Hospital

Am Klinikum 1, 07747 Jena, Germany

Universitäts-Herzzentrum Bad Krozingen, Germany

Südring 15, 79189 Bad Krozingen, Germany

Middle East

  1. University of Alexandria, Egypt
  2. Rambam Medical Center, Haifa, Israel
  3. Queen Alia Heart Institute, Amman, Jordan
  4. Rambam Health Care Campus, Israel*
University of Alexandria, Egypt

University of Alexandria, Egypt

Rambam Medical Center, Haifa, Israel

Rambam Medical Center, Haifa, Israel

Queen Alia Heart Institute, Amman Jordan

Queen Alia Heart Institute, Amman, Jordan

Europe – Others

  1. Maastricht University Medical Centre, Maastricht, the Netherlands*
  2. Cardiac Surgery, University Hospitals Leuven, Belgium.
  3. Golden Jubilee National Hospital, Clydebank, Glasgow, Scotland, UK.
  4. University of Bristol, UK.
  5. Royal Infirmary of Edinburgh, UK.
  6. Praceta Mota Pinto, Coimbra, Portugal*
  7. Centro Hospitalar e Universitário São João, Portugal
  8. Centro Hospitalar Lisboa Ocidental, Portugal
  9. Henry Dunant Hospital Center, Athens, Greece.
  10. Dedinje Cardiovascular Inst Belgrade
  11. University Hospital Dubrava, Croatia*
  12. Medical University of Silesia (Katowice), Poland
  13. General University Hospital, Prague
  14. Zbigniew Religa Lower Silesian Heart Disease Centre – Medinet, Poland*
  15. University Hradec Králové, Czech Republic*
  16. University of Leicester, UK
  17. Federal Center for Cardiovascular Surgery, Penza, Russia
  18. Dedinje Cardiovascular Institute, Serbia
Maastricht University Medical Centre, Maastricht, the Netherlands

Maastricht University Medical Centre, Maastricht, the Netherlands

Thoraxcenter, Erasmus MC, Rotterdam, the Netherlands

Thoraxcenter, Erasmus MC, Rotterdam, the Netherlands

Cardiac Surgery, University Hospitals Leuven, Belgium

Cardiac Surgery, University Hospitals Leuven, Belgium

Golden Jubilee National Hospital, Clydebank, Glasgow, Scotland, UK

Golden Jubilee National Hospital, Clydebank, Glasgow, Scotland, UK

University of Bristol, UK

University of Bristol, UK

Royal Infirmary of Edinburgh, UK

Royal Infirmary Edinburgh, Little France Crescent, Edinburgh, UK

Praceta Mota Pinto, Coimbra, Portugal

Praceta Mota Pinto, Coimbra, Portugal

Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland

Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland

Henry Dunant Hospital Center, Athens, Greece

Henry Dunant Hospital Center, Athens, Greece

Hospital Cruz Vermelha, Lisbob, Portugal

Hospital Cruz Vermelha, Lisbob, Portugal

Centro Hospitalar e Universitário São João, Portugal

Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal

Centro Hospitalar Lisboa Ocidental, Portugal

Av. Prof. Dr. Reinaldo dos Santos, 2790-134 Carnaxide, Portugal

Dedinje Cardiovascular Inst Belgrade

Heroja Milana Tepića 1, Beograd, Serbia

University Hospital Dubrava, Croatia

Avenija Gojka Šuška 6, 10000, Zagreb, Croatia

Medical University of Silesia (Katowice), Poland

Poniatowskiego 15, 40-055 Katowice, Poland

General University Hospital, Prague

1, Na Bojišti 1771, Nové Město, 120 00 Praha-Praha 2, Czechia

Zbigniew Religa Lower Silesian Heart Disease Centre – Medinet, Poland

Marii Skłodowskiej-Curie 9, 41-800 Zabrze, Poland

University Hradec Králové, Czech Republic

Rokitanského 62/26, 500 03 Hradec Králové, Czechia

University of Leicester, UK

University Rd, Leicester LE1 7RH, UK

Rambam Health Care Campus, Israel

HaAliya HaShniya St 8, Haifa, 3109601, Israel

Spain

  1. Hospital Univeritario Del Vinalopo, Spain
  2. Hospital Clinic de Barcelona (ICCV), Spain
  3. NavarraBiomed, Spain
Hospital Clinic de Barcelona (ICCV), Spain

C. de Villarroel, 170, 08036 Barcelona, Spain

Hospital Univeritario Del Vinalopo, Spain

Carrer Tonico Sansano Mora, 14, 03293 Elx, Alicante, Spain

Hospital Universitario de Navarra, Spain

C. de Irunlarrea, 3, 31008 Pamplona, Navarra, Spain

Austria

  1. Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria.*
  2. MU Vienna Austria*
  3. Krankenhaus Nord Vienna North Hospital, Austria*
  4. Medical University of Graz, Austria*
Department of Cardiac Surgery University of Vienna, Austria

Department of Cardiac Surgery University of Vienna, Austria

Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria

Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria

Krankenhaus Nord Vienna North Hospital, Austria

Brünner Str. 70/2/401, 1210 Wien, Austria

MU Vienna Austria

Saint Josefskirche, Am Kahlenberg 1, 1190 Wien, Austria

Medical University of Graz, Austria

Auenbruggerpl. 2, 8036 Graz, Austria

Southern America

  1. Fundacardio Foundation, Valencia, Venezuela
  2. National Institute of Cardiology, Mexico City
  3. Heart Institute of São Paulo Medical School, Brazil
  4. Institute of Cardiology, Porto Alegre – RS, Brazil*
  5. Instituto Dante Pazzanese de Cardiologia, Brazil*
Fundacardio Foundation, Valencia, Venezuela

Fundacardio Foundation, Valencia, Venezuela

National Institute of Cardiology, Mexico City

National Institute of Cardiology, Mexico City

Heart Institute of São Paulo Medical School, Brazil

Heart Institute of São Paulo Medical School, Brazil

Institute of Cardiology, Porto Alegre – RS, Brazil

R. Vicente da Fontoura, 2847 – Bela Vista, Porto Alegre – RS, 90460-065, Brazil

Instituto Dante Pazzanese de Cardiologia, Brazil

Av. Dr. Dante Pazzanese, 500 – Vila Mariana, São Paulo – SP, 04012-909, Brazil

The ROMA Trial